Research Article
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Article title
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Abstract
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Keywords
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Introduction
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Experimental
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Materials and methods
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Preparation of raft-forming PEC
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Evaluation of the raft-forming system
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Assessment of entrapment efficiency and percent drug loading
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Determination % yield
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Assessment of in vitro buoyancy
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Measurement of raft strength
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Raft weight and volume
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In vitro dissolution studies
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Variables affecting the release of Ond. HCl
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Effect of (Chitosan - Sod. alginate) ratio
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Effect of anionic polymer type
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Effect of cross-linking agent percentage
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Effect of cross-linking agent
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Effect of non-ionic polymer on Chitosan - Ond. HCl complex
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Swelling study
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Modeling of kinetic drug release
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Determination of optimized formulation
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Morphological examination
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Differential scanning calorimetry
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Fourier transforms infrared spectroscopy (FTIR)
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Analytical statistics
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Results and discussion
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Assessment of the raft formation system
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Raft weight, volume, and strength
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Variables affecting polyelectrolyte complex raft formulation
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Effect of changing polymer ratio of complex
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Effect of anionic polymer type
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Effect of cross-linking agent percentage
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Effect of cross-linking agent
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Effect of addition of non-ionic polymer on Chitosan - Ond. HCl complex
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Swelling study
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Examination of the mathematical framework for kinetic drug release
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Choosing the optimal formula
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Scanning electron microscopy (FE-SEM)
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Differential scanning colorimetric
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Fourier transform infrared spectroscopy (FT-IR)
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Conclusion
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Acknowledgements
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Additional information
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References
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