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  • Article title
  • Abstract
  • Keywords
  • Introduction
  • Materials and methods
    • Chemicals and reagents
    • Preparation of stock solutions and mixed stock solutions
    • Preparation of working solutions
    • Preparation of internal standard solution
    • Preparation of calibration and quality control solutions for the plasma assay
    • Sample preparation
    • Chromatographic conditions
  • Results and discussion
    • Method development and optimization
    • Method validation
    • Selectivity
    • System suitability tests
    • Linearity and range
    • Accuracy and precision
    • Limit of detection (LOD) and limit of quantification (LOQ)
    • Plasma samples
    • Comparison with published methods
  • Conclusion
  • Acknowledgements
  • References
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