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Article title
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Abstract
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Keywords
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Introduction
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The function and structure of the skin
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Abbreviations
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Drug delivery across the skin
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Transdermal drug delivery
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Background on microneedles and mechanism of action
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Advantages of microneedles
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Disadvantages of microneedles
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Types of microneedles
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Solid, non-coated microneedles
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Coated microneedles
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Hollow microneedles
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Dissolvable microneedles
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Swellable microneedles
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Delivery strategies assisted by microneedles
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Materials used in microneedles fabrication
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Silicon
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Metals
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Glass
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Ceramics
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Polymers
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Sugars
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Microneedles manufacturing methods
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Laser ablation
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Lithography
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Micro-molding
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Injection molding
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Additive manufacturing
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Mechanical characterization of microneedles
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Clinical trials on microneedles
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Microneedles and Covid-19 pandemic
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Microneedles in the market, challenges and future outlook
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Conclusions
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References
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