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  • Article title
  • Abstract
  • Keywords
  • Introduction
  • Materials and methods
    • Plant collection
    • Extracts preparation
    • Determination of total phenol content
    • Determination of total flavonoid content
    • Phytochemical analysis of ethyl acetate extract using LC-MS analysis
    • Antioxidant activity (DPPH assay)
    • In vitro evaluation of antiproliferative activity
      • Cell lines and cell culture conditions
      • Antiproliferative assay
    • In vivo evaluation of the antitumor activity
      • Animals
      • Acute toxicity of L. ovalifolium ethyl acetate extract
      • Antitumor activity in an animal model
      • Assessment of kidney and liver functions in the experimental animals
    • Statistical analysis
  • Results and discussion
  • Conclusion
  • References
  • Supplementary material
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