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  • Article title
  • Abstract
  • Keywords
  • Introduction
  • Materials and methods
    • Materials
    • Animal study - ethical approval
    • Preparation of CEZO
    • Design of animal experiment
    • Blood, serum, plasma, and tissue isolation
    • Protein Isolation and sandwich Enzyme-Linked Immunoassay (ELISA) for measurement of NO, IL-6, TNF-α, dan MMP-9
    • Statistical analysis
  • Results and discussion
    • Edema profile in MIA rats model and after treatment
    • Effect on hematology evaluation
    • Effect of spleen weight
    • Effect on IL-6 level and TNF-α concentration
    • Effect on MMP-9 level
  • Conclusion
  • Conflicts of Interest
  • Acknowledgements
  • References
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