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  • ContentsContents
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  • Article title
  • Abstract
  • Keywords
  • Introduction
  • SLNs versus NLCs
  • Types of SLNs and NLCs
  • Types of SLNs
    • Type I (Homogeneous matrix model)
    • Type II (Drug enriched shell model)
    • Type III (Drug enriched core model)
  • Types of NLCs
    • Imperfect type (Imperfectly structured solid matrix)
    • Amorphous type (Structureless solid amorphous matrix)
    • Multiple types (Multiple oils in fat in water)
  • Methods of preparation
    • High energy approaches
    • High-Pressure Homogenization (HPH) method
    • Hot High-Pressure Homogenization (HHPH) method
    • Cold High-Pressure Homogenization (CHPH) method
    • High Shear Homogenization (HSH) and/or ultrasonication (US) method
    • Low-energy approaches
    • Microemulsion (MM) technique
    • Membrane contactor (MC) technique
    • Phase inversion temperature (PIT) technique
    • Coacervation (CV) technique
    • Double emulsion (DE) technique
    • Microemulsion cooling (MEC) technique
  • Approaches with organic solvents
    • Emulsification solvent-evaporation (ESE) technique
    • Emulsification solvent-diffusion (ESD) technique
    • Solvent injection (SI) technique
    • Supercritical fluid (SCF) technique
    • Particle from Gas Saturated Solution (PGSS) method and Gas Assisted Melting Atomization (GAMA) method
  • Drug release
  • Conclusion
  • Conflict of interest
  • Acknowledgements
  • References
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