A, B. Effect of ibudilast and sulfasalazine on (A) disease activity index (DAI) and (B) macroscopic colonic scores (MAC). Data presented as mean ± SD for experimental groups. (***p < 0.001versus control group); and (###p < 0.001versus AA group). AA= acetic acid; C, D. Effect of ibudilast and sulfasalazine on (C) myeloperoxidase activity (MPO), and (D) histopathological changes score. Data presented as mean ± SD for experimental groups. (***p < 0.001versus control group); and (###p < 0.001versus AA group). AA= acetic acid.

 
 
  Part of: Oubaid EN, Abu-Raghif A, Al-Sudani IM (2023) Ibudilast ameliorates experimentally induced colitis in rats via down-regulation of proinflammatory cytokines and myeloperoxidase enzyme activity. Pharmacia 70(1): 187-195. https://doi.org/10.3897/pharmacia.70.e98715