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  • Article title
  • Abstract
  • Keywords
  • Introduction
  • Materials and methods
    • Animals
    • Drugs and chemicals
    • Induction of colitis
    • Experimental design
    • Methods
      • Assessment of disease activity index (DAI)
      • Assessment of macroscopic colonic score (MAC)
      • Measurement of myeloperoxidase (MPO) activity
      • Histopathological and immunohistochemical (IHC) study
      • Statistical analysis
  • Results
    • Effect of ibudilast on DAI
    • Effect of ibudilast on the macroscopic colonic score (MAC)
    • Effect of ibudilast on MPO activity
    • Effect of ibudilast on histopathological changes in rat colonic tissues
    • Effect of ibudilast on proinflammatory cytokines (TNF-α and IL-1β)
  • Discussion
  • Conclusion
  • References
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