A. Effect of lacosamide (LCM) and topiramate (TPM) treatment on the number of horizontal movements in a PTZ-kindling model. *p < 0.05, **p < 0.01 compared to the C-veh group; ##p < 0.01, ###p < 0.001 compared to the LCM group; oop < 0.01 compared to the TPM group. B. Effect of lacosamide (LCM) and topiramate (TPM) treatment on the number of vertical movements in a PTZ-kindling model. ***p < 0.001 compared to the C-veh group; ###p < 0.001 compared to the LCM group.

 
 
  Part of: Shishmanova-Doseva M (2022) Protective effect of lacosamide and topiramate treatment against Pentylenetetrazole-induced kindling and associated cognitive dysfunction in rats. Pharmacia 69(4): 1005-1012. https://doi.org/10.3897/pharmacia.69.e96185