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  • Article title
  • Abstract
  • Keywords
  • Introduction
  • Materials and methods
    • Chemicals
    • Plant collection and extraction
    • The quality control standardization of crude drugs and crude extracts
    • Phytochemical analysis
    • High Performance Thin Layer Chromatography (HPTLC) analysis
      • Preparation of standard compound and extract
      • Chromatographic condition
    • Liquid Chromatography-High Resolution Mass Spectrometer (LC-HRMS) analysis
      • Preparation of sample
      • Angiotensin-Converting Enzyme (ACE) inhibitory activity
    • Statistical analysis
  • Results and discussion
    • The quality control standardization of crude drugs and crude extracts
    • Macro- and microscopic description of Noni’s fruit crude drug
    • Preliminary phytochemical screening
    • Physicochemical, heavy metal contaminant and microbial contaminant analysis
    • Analysis of scopoletin content in the extract by HPTLC
    • Phytochemical analysis using LC-HRMS
    • Determination of in vitro ACE inhibitory activity
  • Conclusion
  • Author contribution
  • Acknowledgements
  • References
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