Synthesis, docking study, and structure-activity relationship of novel niflumic acid derivatives acting as anticancer agents by inhibiting VEGFR or EGFR tyrosine kinase activities


	Compound 3A docked in VEGFR tyrosine kinase, hydrogen bonds (green lines), the pi interactions are depicted in purple lines, and the mapping surface proves compound 3A directly binds to the active pocket of VEGFR tyrosine kinase.

Part of: Yaseen Y, Kubba A, Shihab W, Tahtamouni L (2022) Synthesis, docking study, and structure-activity relationship of novel niflumic acid derivatives acting as anticancer agents by inhibiting VEGFR or EGFR tyrosine kinase activities. Pharmacia 69(3): 595-614. https://doi.org/10.3897/pharmacia.69.e86504