The 2D docking of compounds (HB1-6) against EGFR tyrosine kinase focusing on the interacting amino acids. H-bonds are shown in green dashed lines, and the pi interactions are shown in purple, orange, and pink dashed lines. Superimposition of each compound with erlotinib inside EGFR tyrosine kinase target site is shown.

 
 
  Part of: Alsaad H, Kubba A, Tahtamouni LH, Hamzah AH (2022) Synthesis, docking study, and structure activity relationship of novel anti-tumor 1, 2, 4 triazole derivatives incorporating 2-(2, 3- dimethyl aminobenzoic acid) moiety. Pharmacia 69(2): 415-428. https://doi.org/10.3897/pharmacia.69.e83158