Effect of INT 747 on prostate cancer cell proliferation. (A) Time course dose-response curves for PC-3 cells treated with INT 747 for determinations of IC50. (B) Dose response plots of INT 747, alone and combined with the FXR antagonist, GS, on PC-3 cell lines after 48 h exposure, as detected by MTT assay.

 
 
  Part of: Al-khfajy WS, Arif IS, Al-sudani BT (2022) Synergistic effect of obeticholic acid and fasting-mimicking on proliferative, migration, and survival signaling in prostate cancer. Pharmacia 69(2): 579-587. https://doi.org/10.3897/pharmacia.69.e81452