Various shapes of system self-assembled structures during 40 ns simulation time. Part of phospholipids was presented by: light blue beads for ethanolamine head groups, purple beads for serine head groups, light brown beads for phosphate, pink beads for glycerol backbone, and dark brown beads for hydrocarbon tail group. cholesterol was presented by dark blue beads, whereas yellow beads presented vitamin c and water molecules were lime beads. a Liposome of system 220LiPE-88Chol-10VitC at t = 21.88 ns (lifetime of liposome = 21.8 - 40 ns). Cholesterol was encapsulated in liposome bilayer (hydrophobic part of liposomes), meanwhile vitamin C was encapsulated in the core of liposome (hydrophilic part of liposomes) along with water molecules b Planar bilayer of system 220DOPE-0Chol-10VitC at t = 40 ns (the end of the simulation). c Disc-like bilayer of system 220DLiPS-33Chol-10VitC at t= 40 ns. Unlike liposome, there were no core formed and no water encapsulated in self-assembled structure. d Toroidal bilayer of system 220DLPS-0Chol-10VitC at t = 40 ns. e A curved bilayer of system 220DOPE-33Chol-10VitC at t = 40 ns.

 
 
  Part of: Hudiyanti D, Christa SM, Mardhiyyah NH, Anugrah DSB, Widiarih T, Siahaan P (2022) Dynamics insights into aggregation of phospholipid species with cholesterol and vitamin C. Pharmacia 69(2): 385-391. https://doi.org/10.3897/pharmacia.69.e81435