Hyperlipidaemia associated with modulation of vascular endothelial markers. Comparison between result analysed from serum of healthy and patient group indicated that Hyperlipidaemia reduced arylesterase (AE) and nitric oxide (NO) together with increase peroxidae (PO), arginase (AG), metalloendopeptidase (MEP), myeloperoxidase (MPO), and peroxynitrite (PN). Data expressed as mean±SD, *p<0.001.