Compound 7 induces apoptosis in MCF-7 breast cancer cells. A) Fluorescence images of MCF-7 breast cancer cells showing fragmented nuclei after DAPI staining. Scale bar: 10 µm, B) Detection of DNA fragmentation by agarose gel electrophoresis. Cells were treated and genomic DNA was extracted and electrophoresed on 1.5% agarose gels. M: DNA molecular weight marker; C: vehicle-treated control cells; 5%: 5% DMSO-treated cells; 7: Compound 7-treated cells. Three experiments were performed with similar results.

 
 
  Part of: Al-Bayati AI, Mahmood AAR, Al-Mazaydeh ZA, Rammaha MS, Al-bayati RI, Alsoubani F, Tahtamouni LH (2021) Synthesis, docking study, and in vitro anticancer evaluation of new flufenamic acid derivatives. Pharmacia 68(2): 449-461. https://doi.org/10.3897/pharmacia.68.e66788