Alpha-glucosidase enzyme inhibting activity ((IC50(µM) of palmatine, glimepiride, metformin and standard drug(acarbose). The result are shown as Mean ± standard deviation in triplicates (n = 3). The data were statistically analyzed by One-way ANOVA followed by Dunnet’s post hoc test. Graph showed that acarbose(a) vs. glimepiride = p < 0.0001 = d; acarbose vs. metformin = p < 0.0001 = d; acarbose vs. palmatine = p < 0.0001 = d. Glimepiride vs. metformin = No significant = d, glimepiride vs. palmatine = No significant = d and metformin vs. palmatine = No significant = d.

 
 
  Part of: Okechukwu P, Sharma M, Tan WH, Chan HK, Chirara K, Gaurav A, Al-Nema M (2020) In-vitro antidiabetic activity and in-silico studies of the binding energies of palmatine and the standard compounds with the three receptors of alpha amylase, alpha glucosidase, and DPP-IV enzyme. Pharmacia 67(4): 363-371. https://doi.org/10.3897/pharmacia.67.e58392