In-vitro anti-diabetic activity and in-silico studies of binding energies of palmatine with alpha-amylase, alpha-glucosidase and DPP-IV enzymes

Patrick Okechukwu; Mridula  Sharma; Wen Hui Tan; Hor Kuan Chan; Kavita Chirara; Anand  Gaurav; Mayasah  Al-Nema

doi:10.3897/pharmacia.67.e58392

Zhaoling Hou, Yan Jin, Yuxin Li, Hushuai Fan, Chaoni Xiao, Qian Li, Yajun Zhang (2022)
Immobilization of peroxisome proliferator-activated receptor gamma and the application in screening modulators of the receptor from herbal medicine. Journal of Chromatography B 1190: 123098.

DOI: 10.1016/j.jchromb.2022.123098

Edson D. Hernández‐Velázquez, Mayra D. Herrera, Clara Alba‐Betancourt, Pedro Navarro‐Santos, Rafael Ortíz‐Alvarado, César R. Solorio‐Alvarado (2023)
Synthesis and in vivo Evaluation of Fluorobenzyl Metformin Derivatives as Potential Drugs in The Diabetes Treatment. Asian Journal of Organic Chemistry 12: .

DOI: 10.1002/ajoc.202300200

Hanan Y. Aati, Mariyam Anwar, Jawaher Al-Qahtani, Areej Al-Taweel, Kashif-ur-Rehman Khan, Sultan Aati, Faisal Usman, Bilal Ahmad Ghalloo, Hafiz Muhammad Asif, Jafir Hussain Shirazi, Aliza Abbasi (2022)
Phytochemical Profiling, In Vitro Biological Activities, and In-Silico Studies of Ficus vasta Forssk.: An Unexplored Plant. Antibiotics 11: 1155.

DOI: 10.3390/antibiotics11091155

SREEJA S., ANTON SMITH A., MADAN S., SUNILKUMAR D., VANI V. (2021)
COMPUTATIONAL MOLECULAR MODELLING OF 2-AMINOBENZIMIDAZOLE DERIVATIVES: STRONG SUCCESSOR OF HYPOGLYCAEMIC AGENT. International Journal of Pharmacy and Pharmaceutical Sciences : 16.

DOI: 10.22159/ijpps.2021v13i9.41877

Mayasah Al-Nema, Anand Gaurav, Vannajan Sanghiran Lee (2023)
Designing of 2,3-dihydrobenzofuran derivatives as inhibitors of PDE1B using pharmacophore screening, ensemble docking and molecular dynamics approach. Computers in Biology and Medicine 159: 106869.

DOI: 10.1016/j.compbiomed.2023.106869

Mayasah Al-Nema, Anand Gaurav, Vannajan Sanghiran Lee, Baskaran Gunasekaran, Ming Tatt Lee, Patrick Okechukwu (2021)
Identification of dual inhibitor of phosphodiesterase 1B/10A using structure-based drug design approach. Journal of Molecular Liquids 342: 117485.

DOI: 10.1016/j.molliq.2021.117485

Okechukwu Patrick Nwabueze, Mridula Sharma, Abbirami Balachandran, Anand Gaurav, Anis Najwa Abdul Rani, Jeleń Małgorzata, Morak-Młodawska Beata, Charlie A. Lavilla, Merell P. Billacura (2022)
Comparative Studies of Palmatine with Metformin and Glimepiride on the Modulation of Insulin Dependent Signaling Pathway In Vitro, In Vivo & Ex Vivo. Pharmaceuticals 15: 1317.

DOI: 10.3390/ph15111317

Bikash Adhikari, Andrea Mastinu (2021)
Roles of Alkaloids from Medicinal Plants in the Management of Diabetes Mellitus. Journal of Chemistry 2021: 1.

DOI: 10.1155/2021/2691525

Pullikaparambil Sasidharan Unnikrishnan, Andhere Animish, Gunabalan Madhumitha, Krishnamurthy Suthindhiran, Mangalam Achuthananthan Jayasri (2022)
Bioactivity Guided Study for the Isolation and Identification of Antidiabetic Compounds from Edible Seaweed—Ulva reticulata. Molecules 27: 8827.

DOI: 10.3390/molecules27248827