4-aminopyridine – the new old drug for the treatment of neurodegenerative diseases

Ivanka Kostadinova; Nikolai Danchev

doi:10.3897/pharmacia.66.e35976

Research Article

Pharmacia 66(2): 67-74
https://doi.org/10.3897/pharmacia.66.e35976 (23 Jul 2019)

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Neuroprotective effect of newly synthesized 4-aminopyridine derivatives on cuprizone-induced demyelination in mice—a behavioral and immunohistochemical study. Amino Acids 53: 1279.

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Radiochemical Synthesis and Evaluation of 3-[11C]Methyl-4-aminopyridine in Rodents and Nonhuman Primates for Imaging Potassium Channels in the CNS. ACS Chemical Neuroscience 13: 3342.

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Hydrogen Ion Dynamics as the Fundamental Link between Neurodegenerative Diseases and Cancer: Its Application to the Therapeutics of Neurodegenerative Diseases with Special Emphasis on Multiple Sclerosis. International Journal of Molecular Sciences 23: 2454.

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A. S. Krylov, Yu. L. Piterskaya, V. V. Gurzhiy, D. Yu. Voronina, A. V. Dogadina (2022)
Synthesis of Phosphoramidates Based on Aminopyridines. Russian Journal of General Chemistry 92: 1912.

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The Computational Study, 3D-QSAR, and Molecular Docking Study of 2-Amino 5-Methyl Pyridine. Polycyclic Aromatic Compounds 43: 1495.

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Synthesis, characterization, potential antimicrobial, antioxidant, anticancer, DNA binding, and molecular docking activities and DFT on novel Co(II), Ni(II), VO(II), Cr(III), and La(III) Schiff base complexes. Applied Organometallic Chemistry 36: .

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Exploring the Versatility of 4-Aminopyridine and Its Analogues in Managing Demyelinating Diseases (A Review). Russian Journal of Bioorganic Chemistry 50: 824.

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