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  • Article title
  • Abstract
  • Keywords
  • Introduction
  • Materials and methods
    • Raw material, authentication, and chemicals
    • Experimental design
    • Extraction procedures and concentration
    • Raw-material characterization and preliminary phytochemical screening
    • Total phenolic and total flavonoid contents
    • DPPH radical-scavenging activity
    • Statistical analysis, optimization, and validation
  • Results
    • Raw-material authentication and preliminary characteristics
    • Preliminary phytochemical profile
    • Observed extraction responses
    • Model adequacy and factor effects
    • Descriptive matched center-point assessment
    • Multi-response optimization and validation
    • Yield-normalized phenolic- and flavonoid-equivalent recovery
  • Discussion
    • Method-specific extraction behavior
    • Yield-quality trade-off
    • Interpretation of matched center points
    • Statistical reliability and model limitations
    • Preliminary characterization and study limitations
    • Practical implications
  • Conclusion
  • Acknowledgments
  • References
  • Additional information
    • Conflict of interest
    • Ethical statements
    • Artificial Intelligence (AI) use
    • Funding
    • Author contributions
    • Author ORCIDs
    • Data availability
  • Supplementary material
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