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  • Article title
  • Abstract
  • Keywords
  • Introduction
  • Materials and methods
    • Materials
      • Chemicals
    • HPLC system optimization
    • Analytical method validation
    • Optimization of solid-phase extraction system
    • Plasma sample preparation
    • Bioanalytical method validation
    • Comparison with the established method
  • Results and discussion
    • HPLC system optimization
      • OFAT optimization
      • System suitability test
    • Analytical method validation
    • Optimization of solid-phase extraction system
    • Plasma sample preparation
    • Bioanalytical method validation
    • Comparison with the established method
  • Conclusion
  • Additional information
  • References
  • Supplementary material
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