The left panel shows the docking results of sunitinib (stick representation; indicated by a small arrow) to the MERS-CoV PLpro (cartoon representation). MERS-CoV PLpro domains were labeled next to the corresponding domain. The right panel shows a surface representation of the binding pocket of sunitinib (indicated by a small arrow) in the upper box. The lower box shows the interaction residues of PLpro with the sunitinib molecule.

 
 
  Part of: Alaofi AL, Shahid M, Kalam MA (2025) Inhibition of MERS-CoV papain-like protease by sunitinib: In vitro and in silico investigations. Pharmacia 72: 1-12. https://doi.org/10.3897/pharmacia.72.e141634