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  • Article title
  • Abstract
  • Keywords
  • Introduction
  • Materials and methods
    • Chemicals and antibodies
    • Animals and work design
    • Blood sampling and preparation
    • Tissue sampling preparation
    • Disposal of carcasses
    • Determination of biochemical parameters
    • Determination of complete blood count (CBC)
    • Estimation of blood glucose and serum insulin levels
    • Histopathological study
    • Immunofluorescence analysis
    • Ethics approval
    • Statistical analysis
  • Results
    • Effect of different treatments on hematological parameters in STZ-induced T1DM in mice
    • Effect of fond and STZ on liver and kidney toxicity parameters in STZ-induced T1DM in mice
    • Effect of STZ with or without fond on levels of serum insulin and blood glucose
    • Effect of fond on general architectures of pancreatic tissues from STZ-induced T1DM
    • Pancreatic β cells insulin, PAR-2, and fibrinogen protein expression in Fond-treatment with or without STZ
    • Effect of STZ with/without fond on insulin (red fluorescence) and CXCL16 (green fluorescence) pancreatic islet expression using double immunofluorescence analysis
    • Nuclear morphology of pancreatic islets from STZ-treatment with or without fond using DAPI staining
  • Discussion
  • Conclusion
  • Additional information
  • References
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