Computational design and validation of siRNA molecules to silence oncogenic CTNNB1 mRNA as a potential therapeutic strategy against hepatitis B/C virus-associated hepatocellular carcinoma


	RMSD trajectories of the siRNA-Ago2 complexes and the reference miRNA (s0). All siRNA molecules exhibited structural stability to the same extent as the reference miRNA throughout the 100-ns simulation.

Part of: Fajardo LE, Macalalad MA, Odchimar NM, de Guzman JC, Orosco F (2024) Computational design and validation of siRNA molecules to silence oncogenic CTNNB1 mRNA as a potential therapeutic strategy against hepatitis B/C virus-associated hepatocellular carcinoma. Pharmacia 71: 1-14. https://doi.org/10.3897/pharmacia.71.e127981