Computational design and validation of siRNA molecules to silence oncogenic CTNNB1 mRNA as a potential therapeutic strategy against hepatitis B/C virus-associated hepatocellular carcinoma


	Secondary structures of the mRNA-siRNA duplexes and their free energies of binding. A more negative binding energy indicates a stronger interaction between the mRNA and siRNA. A. s3; B. s19; C. s22; D. s28.

Part of: Fajardo LE, Macalalad MA, Odchimar NM, de Guzman JC, Orosco F (2024) Computational design and validation of siRNA molecules to silence oncogenic CTNNB1 mRNA as a potential therapeutic strategy against hepatitis B/C virus-associated hepatocellular carcinoma. Pharmacia 71: 1-14. https://doi.org/10.3897/pharmacia.71.e127981