The top-scored docking pose of compound 8 is superimposed with the X-ray structure of the substrate oligonucleotide (PDB ID: 2DNJ) (Lahm and Suck 1991). The binding site surface is colored as follows: polar regions in red, hydrophobic regions in white, and solvent-exposed regions in cyan.

 
 
  Part of: Marković A, Atanasova M, Buyukliev R, Bakalova A, Šmelcerović A, Cherneva E (2024) 3’-Methyl-4-thio-1H-tetrahydropyranspiro-5’-hydantoin platinum complex as a novel deoxyribonuclease I inhibitor. Pharmacia 71: 1-7. https://doi.org/10.3897/pharmacia.71.e126246