The intermolecular interactions of the top-scored docking pose of compound 8 within the identified binding site on DNase I are depicted. The binding pocket surface color map is as follows: polar regions in red, hydrophobic regions in white, and solvent-exposed regions in cyan. Coordinative bonds in the MOE package are visualized as positively charged atoms.

 
 
  Part of: Marković A, Atanasova M, Buyukliev R, Bakalova A, Šmelcerović A, Cherneva E (2024) 3’-Methyl-4-thio-1H-tetrahydropyranspiro-5’-hydantoin platinum complex as a novel deoxyribonuclease I inhibitor. Pharmacia 71: 1-7. https://doi.org/10.3897/pharmacia.71.e126246