Proposed-biomechanism of tempe on the modulation of cellular antioxidant status via the Nrf2- dependent signaling pathway. Abbreviations: 3HAA: 3-hydroxyanthranilic acid; AKT: protein kinase B; ARE: antioxidant response element; GPx: glutathione peroxidase; GR: glutathione reductase; IFAs: isoflavone aglycones; IFGs: isoflavone glycosides; Keap1: Kelch-like ECH-associated protein 1; Nrf2: nuclear factor erythroid 2-related factor 2; PI3K: phosphoinositide 3-kinase; ROS: reactive oxygen species; RTK: receptor tyrosine kinase; SOD: superoxide dismutase.

 
 
  Part of: Surya R, Amalia N, Gunawan WB, Taslim NA, Ghafoor M, Mayulu N, Hardinsyah H, Abdi Syahputra R, Kartawidjajaputra F, Rizzo G, Tjandrawinata RR, Subali D, Kurniawan R, Nurkolis F (2024) Tempe as superior functional antioxidant food: From biomechanism to future development of soybean-based functional food. Pharmacia 71: 1-7. https://doi.org/10.3897/pharmacia.71.e116748