The effect of VAEE on caspase-3 (A), Bcl-2 (B), p53 (C) expresssion. (N: normal rats, ISO: ISO 85 mg/kgbw ,ISO+QR: ISO 85 mg/kgbw + 100 mg/kgbw quercetin. ISO+VA100: ISO 85 mg/kgbw + 100 mg/kgbw VAEE, ISO+VA300: ISO 85 mg/kgbw + 300 mg/kgbw VAEE, ISO+VA500: ISO 85 mg/kgbw + 500 mg/kgbw VAEE, the data were presented in mean ± standard error of the mean (SEM). (*: p<0,05, **: p<0,01, ***: p<0.001, P>0.05 ns/not significance).

 
 
  Part of: Prananda AT, Dalimunthe A, Harahap U, Syahputra RA, Nugraha SE, Situmorang PC, Fah YT, Adrian, Siahaan JM, Velaro AJ, Bilakaya B, Harahap MAY (2023) Phytochemical profiling and cardioprotective activity of Vernonia amygdalina ethanol extract (VAEE) against ISO-induced cardiotoxicity in rats. Pharmacia 70(3): 758-796. https://doi.org/10.3897/pharmacia.70.e111329