ACE administration increased the level of regulatory T cells in mice fed a high-fat, high-fructose diet for 5 months. The level of regulatory T cell A. CD4+CD25+CD62L+ subsets, B. CD4+CD25+IL-10+ subsets, and C. CD4+CD25+TGF-+subsets of mice fed with HFFD and administration of ACE from flow cytometry analysis. The percentage of regulatory T cell D. CD4+CD25+CD62L+ subsets, E. CD4+CD25+IL-10+ subsets, and F. CD4+CD25+TGF-+ subsets of mice fed with HFFD and administered ACE The data are mean SD (n = 5). N: normal-fed mice (non-high-fat-fructose diet); HFFD: high-fat-fructose diet mice (w/o administration of ACE); D1: HFFD mice receiving ACE 104 mg/kg body weight; D2: HFFD mice receiving ACE 520 mg/kg body weight; D3: HFFD mice receiving ACE 5200 mg/kg body weight. The different notation on the chart was considered significantly different for each group at p<0.05 and vice versa on the DMRT post hoc test.

 
 
  Part of: Nafisah W, Dalilati AZ, Christina YI, Atho’illah MF, Rifa’i M, Noor TNETA, Nugraha AP (2024) Amstirdam coffee ameliorates Lp-PLA2 and the inflammatory response in an atherosclerosis mice. Pharmacia 71: 1-8. https://doi.org/10.3897/pharmacia.71.e106817