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  • Article title
  • Abstract
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  • Introduction
  • The function of epigenetic in personalized medicine design
    • Epigenetic deregulation is a reason for cancer in humans
      • Critical signals can affect epigenetics
      • Epigenetic codes
      • HDAC alteration in driving cancer
      • Abnormal DNA methylation in cancer therapy
    • Epigenetic treatment
  • Pharmacogenomics and personalized medicine
  • Epigenetic alteration of drug-response-related genes and relation to clinical pharmacology
  • DNA methylation with CYP1A1
  • DNA methylation with the regulation of drug transporter
  • DNA methylation of phase II drug metabolizing enzymes (DMEs)
  • DNA methylation of drug targets and signal pathway genes
  • Methylation pharmacogenetics
    • Thiopurine methyltransferase as a model system
    • DNA methylation-related SNPs in pharmacogenomics
  • What is new and conclusion?
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